top of page

Welcome to CLEANTheory
grow. truly. clean. 

Cannabis cultivation, chlorine dioxide
Helping agriculture and indoor cultivation deliver clean, compliant products to customers, healthier facilities for staff, and acceleration to the bottom line.
Founding Principles
Cannabis cultivation, chlorine dioxide

Founded by risk management, data and science experts

CLEANTheory is a leading science and data-driven biosecurity platform that consistently suppresses disease-causing pathogens, eliminates unwanted odor, maximizes operational efficiency, and increases profitability.  



Average client monthly spend per square foot of Critical Space 



Average client monthly revenue increase per sq ft of Critical Space


1-Individual results may vary.

2-As of 2/21/2022. In an internal study, CLEANTheory analyzed the average amount of subscription fees paid per client per square foot per month in contrast to the amount of additional net revenue that a client reported was directly attributable to their use of the CLEANTheory platform compared to their average over the preceding twelve-months.  "Critical Space" is facility square footage, as determined by CLEANTheory, to be treated daily.   Individual results may vary.

ClO2 size comparison (9)_edited.png

Disinfection is centuries old,

Common methods rely upon chemicals sold through catalogs or non-technical salespeople.  So-called "disinfection devices" don't require EPA validation for safety or efficacy and are long on promises and short on real-world science.  "Studies" too limited in their ability to quantify true risk and replicate real-world conditions are foisted upon unsuspecting key stakeholders.  Glossy brochures and far-fetched claims just don't cut it when it comes to the health of plants and the people that tend to them.

but little has been done to assure it for indoor cultivation.

Cultivation Pressures
Cannabis cultivation, chlorine dioxide

Unsurprisingly, the average cultivator loses 20%-40%

of yield to disease, costing millions of dollars of lost revenue...even when an operation is profitable.  Supply chain interruptions, increasing regulations, global competition, industry consolidation, and changing consumer habits all put downward pressure on current and future profitability.  With a smarter biosecurity model, the average operator could increase revenues through fewer yield losses, recoup labor costs and provide safer working conditions. 



#1 response in
the survey
Operators who identify pest & disease control as their biggest challenge


Line image for website homepage.png

< 3%

Operators who identify pest & disease control as technology they're automating


ClO2 size comparison (10)_edited.png

If pest & disease control is the #1 concern of growers, why do so few automate it?

3-As of 1/1/2022.  In an internal study, CLEANTheory's poll of prospective and current clients demonstrates a 20%-40% average yield loss to disease.  This loss

includes legally remediated products.

4-Cultivation Industry Report, CBT, 2021

Wavy Abstract Background

IoT, AI, and big data are altering industries,

 old and new alike. From the technology that's in your hand to autonomous vehicles, to apps and programs that adapt and continuously improve, the world both big and small is changing at the speed of innovation.

A New Model
Image by Noita Digital
Dark Blue Accents Venn Diagram_edited_ed

A new model for cultivation success

ClO2 size comparison (18)_edited_edited_

CLEANTheory has engineered a new model for cultivation success by improving upon the traditional formula for disinfection (dubbed the "Four C's").  First, we use proprietary chemistry unmatched in combined efficacy and safety.  Then, we add a specific frequency and timing of treatment (consistency).  Lastly, a verification protocol (certainty) determines treatment efficacy.  These are the new "Six C's" redefining how operators fight disease and unwanted odor.


We effortlessly serve any size grow, from thousands to millions of square feet.

5-Source: The Four C's 

CLEANTheory model vs traditional biosecurity models

Graphs for website home page.png

75% - 90%
Less labor

effort for best practices

75% +
Increase in passed tests for microbials


CT logo Questrial.png


CT logo Questrial.png

This new model means less time and money spent to sanitize and disinfect facilities while, at the same time, passing more tests for microbials means healthier plants.  And by automating the entire process you can now save tens to hundreds of thousands of dollars on annual labor costs while reducing or even eliminating the most common sanitation-related employee injuries.

Based on two internal studies. In the first, CLEANTheory performed sanitation duties using the equipment included in the platform and compared it against the replication of traditional methods which included preparation, dilution, transfer, and spraying.  The results represent the average rate of improvement exhibited by CLEANTheory's platform against traditional methods.  In the second, CLEANTheory analyzed client data prior to and after the use of the platform and the results represent an average increase in the number of passed microbial tests while using CLEANTheory in comparison to the prior 12-month historical period before the client's use of the platform.  Individual results may vary.  

ClO2 size comparison (20).png

Meet our leadership team


Christian Castiglione

Co-founder & CEO


Kyle Baker

Co-founder & 
Chief Strategy Officer

dav glass_edited.jpg

Dav Glass


Meet our advisors


Lezli Engleking

International Standards


Dr. Greg Gerdeman

Neuroscience & Biomedical Research


Matt Harrison

Agricultural Consulting

dr welke.jpg

Dr. Richard Welke

Method Engineering

Meet our platform partners

ClO2 size comparison (19).png
purafil logo_edited.png
BLC logo_edited.png
bottom of page